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DeCS
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Descriptor English:
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Neuritis, Autoimmune, Experimental
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Descriptor Spanish:
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Neuritis Autoinmune Experimental
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Descriptor Portuguese:
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Neurite Autoimune Experimental
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Synonyms English:
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Allergic Neuritis, Experimental
Autoimmune Neuritis, Experimental
Autoimmune Neuropathies, Experimental
Autoimmune Neuropathy, Experimental
EAN (Experimental Allergic Neuritis)
EAN (Experimental Autoimmune Neuritis)
Experimental Allergic Neuritis
Experimental Autoimmune Neuritis
Experimental Autoimmune Neuropathies
Experimental Autoimmune Neuropathy
Neuritis, Experimental Allergic
Neuritis, Experimental Autoimmune
Neuropathies, Experimental Autoimmune
Neuropathy, Experimental Autoimmune
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Tree Number:
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C10.114.703.700
C10.668.829.650.500
C20.111.258.625.700
E05.598.500.500.875
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Definition English:
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An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52) |
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Indexing Annotation English:
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coordinate with GUILLAINE-BARRE SYNDROME if pertinent
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History Note English:
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2005 (1982)
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Allowable Qualifiers English:
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Record Number:
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9637
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Unique Identifier:
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D009444
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Occurrence in VHL:
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Similar:
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DeCS
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